Parental thermal environment controls the offspring phenotype in Brook charr (Salvelinus fontinalis): insights from a transcriptomic study

Banousse, Ghizlane ORCID: https://orcid.org/0009-0004-9769-5343, Normandeau, Eric, Semeniuk, Christina, Bernatchez, Louis et Audet, Céline ORCID: https://orcid.org/0000-0003-3366-210X (2024). Parental thermal environment controls the offspring phenotype in Brook charr (Salvelinus fontinalis): insights from a transcriptomic study. G3 Genes|Genomes|Genetics . jkae051.

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Résumé

Brook charr is a cold-water species which is highly sensitive to increased water temperatures, such as those associated with climate change. Environmental variation can potentially induce phenotypic changes that are inherited across generations, for instance, via epigenetic mechanisms. Here, we tested whether parental thermal regimes (intergenerational plasticity) and offspring-rearing temperatures (within-generational plasticity) modify the brain transcriptome of Brook charr progeny (fry stage). Parents were exposed to either cold or warm temperatures during final gonad maturation and their progeny were reared at 5 or 8 °C during the first stages of development. Illumina Novaseq6000 was used to sequence the brain transcriptome at the yolk sac resorption stage. The number of differentially expressed genes was very low when comparing fry reared at different temperatures (79 differentially expressed genes). In contrast, 9,050 differentially expressed genes were significantly differentially expressed between fry issued from parents exposed to either cold or warm temperatures. There was a significant downregulation of processes related to neural and synaptic activity in fry originating from the warm parental group vs fry from the cold parental one. We also observed significant upregulation of DNA methylation genes and of the most salient processes associated with compensation to warming, such as metabolism, cellular response to stress, and adaptive immunity. -- Keywords : Brook charr ; epigenetics ; brain ; fry ; temperature.

Type de document :	Article
Validation par les pairs :	Oui
Information complémentaire :	Les données brutes liées à cet article sont disponibles dans DFDR: https://doi.org/10.20383/103.0894
Mots-clés :	Omble de fontaine ; Réchauffement de la Terre ; Tolérance thermique (Physiologie) ; Transcriptomique ; Épigénétique.
Version du document déposé :	Version officielle de l'éditeur
Départements et unités départementales :	Institut des sciences de la mer de Rimouski (ISMER)
Déposé par :	DIUQAR UQAR
Date de dépôt :	17 avr. 2024 14:34
Dernière modification :	17 avr. 2024 15:58
URI :	https://semaphore.uqar.ca/id/eprint/2945

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